Dissolution test aim to evaluate the release profile of a drug from the dosage form. It allows anticipating the potential available dose of the drug within a certain period of time once administered.

Last updated on: 24-04-2023 - 15:34

Contact: Jonathan Goole
Organisation: Université Libre de Bruxelles (ULB)
Status: Published in peer reviewed journal
The DPRA is an in chemico method which quantifies the remaining concentration of cysteine- or lysine-containing peptide following 24 hours incubation with the test chemical at 25 +/-2,5ºC. The synthetic peptides contain phenylalanine to aid in the detection. Relative peptide concentration is

Last updated on: 22-02-2022 - 10:59

Contact: Bart Desmedt
Organisation: Sciensano
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)