Dissolution tests

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Scope of the method

The Method relates to
  • Human health
The Method is situated in
  • Basic Research
Type of method
  • In chemico

Description

Method keywords
  • in vitro dissolution testing
  • release profile
  • Target- and drug discovery
  • Correlation in vitro in vivo
Scientific area keywords
  • Pharmacy
  • quality control
  • early stage research
  • Validation
Method description

Dissolution test aim to evaluate the release profile of a drug from the dosage form. It allows anticipating the potential available dose of the drug within a certain period of time once administered.

Lab equipment
  • - UV/visible spectrophotometer,
  • - Dissolution ramp.
Method status
  • Published in peer reviewed journal

Pros, cons & Future potential

Advantages
  • - Fast,
  • - ready to use,
  • - reliable.
Challenges

Very long release systems.

Modifications

No

Future & Other applications

No

Contact person

Jonathan Goole

Organisations

Université Libre de Bruxelles (ULB)
Pharmaceutics and Biopharmaceutics
Belgium