The cardiorespiratory model reproduces human physiology with a high level of fidelity. It is a lumped parameter model including a representation of atria, ventricles, pulmonary and systemic circulations, autonomic controls, metabolic peripheral control, ventilation and gas exchange in tissues and

This white-box model uses energy partitioning throughout the lifetime of dairy animals (growth, lactation, gestation, ...) to simulate reproduction performance, lifetime length, production performance etc. The method is developed by dr. Olivier Martin at INRAE, MoSAR, Paris.

We use stem cell-derived sensory neurons and via a small molecule-based protocol (Young et al, 2014) we derive them into human sensory neurons with a nociceptor phenotype (express somatosensory ion channels).