Accelerating the adoption of organ-on-a-chip technologies

Posted on: 12/07/2020

A report has been published on "Organ-On-A-Chip Technologies (OOAC): Current status and translatability of data". OOAC are also known as "Micro Physiological Systems" (MPS), which provide a  miniaturised physiologically-relevant biological testing system that can be used for academic research and drug discovery.

This report is the result of a workshop in May 2018 where experts from industry, academia and the Medicines and Healthcare products Regulatory Agency discussed the progress and uptake of these technologies as these are not yet routinely used.

Following themes were addressed in the workshop:

  • The use and experiences of this technology in the pharmaceutical industry and CRO communities
  • The development, qualification and translation of the microfluidic and biological systems
  • An appreciation of the regulatory authority viewpoint 
  • A series of real world case studies describing their practical application

The report is written by the Medicines Discovery Catapult, the Medical Research Council (MRC) Centre for Drug Safety Science (CDSS), and the National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) and more information can be found via the NC3Rs website.

organ-on-a-chip, NAM, MPS