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During this training, participants will learn more about novel methodologies genetic toxicology and get hands-on experience with some of these new methods.

During this webinar session, two speakers will give a presentation about the use of NAMs to investigate population variability due to environmental exposure:

• Dr. Shaun McCullough (EPA Center for Public Health and Environmental Assessment) will discuss on the impacts of inter-individual variability using in vitro models evaluation.
• Dr. Chirag Patel (Harvard University) will focus on Data science approaches to discover the determinants of health.

The Swiss 3R Competence Centre is organising a conference day on the 3Rs and more specifically on the following topics:

• 3Rs implementation in practice
• 3Rs innovation and research

The program also includes a poster competition.

Registration via Google form before the 1st of October.

In this webinar, Dr Adrian Biddle (Queen Mary University of London) will share his personal experience of developing an in vitro cancer model for animal replacement in research. Specifically, the following topics will be discussed:

• key considerations when working to replace in vivo animal models
• the benefits of cross disciplinary working and collaboration
• some practical challenges that can arise and approaches to overcome them.

This conference will give an overview of the activities linked to the development of NAMs for chemical safety testing. Conference topics include:

- Variability and Relevance of Traditional Toxicity Tests
- Evolution of Validation and Scientific Confidence Frameworks
- Breakout groups discussing Variability and Relevance of Traditional Toxicity Tests and Feedback on EPA Scientific Confidence Framework

The conference is open to academic scientists, researchers and research scholars. Different topics around Microfluidics and Organs-on-a-Chip will be discussed (e.g. 3D cell culture, toxicity screening, lung-on-a-chip, practical challenges encountered in the development of organs-on-a-chip, etc.). A poster session will also be organised.

Deadline for abstract submission: 16 August 2022

The conference will provide an update on methods in research, development and production for all organoids and tumoroids as well as for organs on chips, through examples and case studies.

Additionally, there will be a round table discussion with the FC3R scientific interest group and the national network of animal welfare structures.

The American Society for Cellular and Computational Toxicology (ASCCT) is organizing its 11^th annual meeting. The meeting will feature the latest science in NAMs and active discussions about the implementation of new science. Topics include:

• Next Generation Risk Assessment
• Decision-Making with NAMs
• Developmental Neurotoxicity
• Human Data for WoE Toxicology
• Integrated Approaches to Testing and Assessment
• Ecotoxicology