UHDR irradiations show healthy tissue sparing effect known as the FLASH effect. Since 2014, the FLASH effect is investigated worldwide to understand how it works and how to trigger it. The FLASH effect is defined as an in vivo effect. However, in vivo models are often expensive and time-consuming.
Last updated on: 05-09-2023 - 08:45
The spatiotemporal distribution of fluorescent compounds was examined during 48 h after immersion (10 µM) or microinjection (2 mg/kg) in the pericardial cavity (PC), intraperitoneally (IP) and yolk sac (IY) of 3 dpf zebrafsh eleuthero-embryos. By modelling the fluorescence of whole-body contours
Last updated on: 01-09-2023 - 09:43
Contact: Marie Pardon
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos
Zebrafish-based platforms have recently emerged as a useful tool for toxicity testing as they combine the advantages of in vitro and in vivo methodologies. Nevertheless, the capacity to metabolically convert xenobiotics by zebrafish eleuthero embryos is supposedly low. To circumvent this concern, a
Last updated on: 01-09-2023 - 09:55
Contact: Marie Pardon
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
The use of patient-derived primary cell cultures in cancer preclinical assays, including drug screens and genotoxic studies, has increased in recent years. However, their translational value is constrained by several limitations, including variability that can be caused by the culture conditions.
Last updated on: 20-07-2023 - 15:05
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to assist the calving process in the cow and how to perform artifical insemination and rectal palpation in cows. Although training on living animals is
Last updated on: 28-06-2023 - 13:53
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: Still in development, History of use, Internally validated
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to handle cows and pigs in a correct and safe way. Although training on living animals is indispensable, a part of the training process can be performed on
Last updated on: 28-06-2023 - 13:53
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: History of use, Internally validated
NMTox is an R-software package and a Shiny app that can be used to explore and subset large datasets and can identify and test for monotonic dose responses. The package was developed within the NanoInformaTIX project where a platform is developed that aims to predict nanomaterial toxicity.
Last updated on: 22-08-2023 - 10:43
Contact: Geert Verheyen
Organisation: Thomas More University of Applied Sciences, University of Hasselt (UHasselt)
Status: Internally validated
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to monitor and approach an animal under anesthesia. Furthermore, they need to learn ventilation techniques and comprehension of an anesthetic machine. An
Last updated on: 23-06-2023 - 17:14
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: History of use, Internally validated
In the skillslab, dummy models and simulators are used for teaching various clinical skills. Endotracheal intubation after induction of anesthesia is an important and commonly performed procedure in veterinary practice. An important part of this training process can be performed on a simulator in
Last updated on: 23-06-2023 - 17:13
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: History of use, Internally validated
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to rescuscitate an animal. A first important part of this training process can be performed on dummy models and simulators in the skillslab.
Last updated on: 23-06-2023 - 17:13
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: Still in development, History of use
