The Colon-on-a-plate® technology is a high-throughput biorelevant in vitro simulation of the physiology and microbiology of the colon. This robust screening technology is not limited to comparing the impact of tens of test product on the microbiome, but also offers insight into the factors

The SHIME® (Simulator of Human Intestinal Microbial Ecosystem) model is currently the most representative in vitro technology for the combined simulation of the physiological, chemical and microbiological properties of the gastrointestinal tract. The model enables study of the impact of long-term

Thyroid hormone system disruption (THSD) has detrimental effects on both human and environmental health. As a rising number of chemicals are reported to interfere with the thyroid hormone system, there is an increasing need for fast and reliable evaluation methods to test for THSD. Currently,

ProDigest's short-term colonic simulation is an in vitro model for rapid screening of the interaction between test products and the gut microbiome. The key microbial saccharolytic and proteolytic markers are analysed as well as evolution in the composition of the microbiome and other endpoints as

The Koken rat is a dummy rat that is developed to train animal procedures, such as handling, blood sampling and intubation.

The cardiorespiratory model reproduces human physiology with a high level of fidelity. It is a lumped parameter model including a representation of atria, ventricles, pulmonary and systemic circulations, autonomic controls, metabolic peripheral control, ventilation and gas exchange in tissues and

This white-box model uses energy partitioning throughout the lifetime of dairy animals (growth, lactation, gestation, ...) to simulate reproduction performance, lifetime length, production performance etc. The method is developed by dr. Olivier Martin at INRAE, MoSAR, Paris.

We use stem cell-derived sensory neurons and via a small molecule-based protocol (Young et al, 2014) we derive them into human sensory neurons with a nociceptor phenotype (express somatosensory ion channels).