Vectra® Polaris™ Automated Quantitative Pathology Imaging System
Commonly used acronym: Polaris
Scope of the method
- Human health
- Basic Research
- Translational - Applied Research
- In vitro - Ex vivo
- Other (e.g. bacteria)
- multiplex immunohistochemistry
- multispectral Imaging
- FFPE tissue sections
- inForm Tissue Finder
- Quantitative pathology
The Vectra® Polaris™ Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
The visualization of multiplex IHC requires a multispectral imaging system.
- Internally validated
Pros, cons & Future potential
State of the art multispectral imaging enables the identification and downstream quantification of multiple overlapping biomarkers (up to 6) without the interference of autofluorescence as the signals are unmixed from one another. Integrated inForm and phenoptr tissue analysis software packages support configurable projects for biomarker quantification and spatial analysis.
The acquisition of a fully automated research stainer is planed in a near futur to standardize the staining.
The Vectra Polaris Automated Quantitative Pathology Imaging System is a cutting-edge tool for cancer immunology research, but also for apoptosis and/or proliferation assays, necrosis and fibrosis using conventional stains, cell cycle characterization, DNA damage determination, inflammation, autoimmune diseases, transplant acceptance, neurodegenerative diseases, and many more!
References, associated documents and other information
Contact personSoizic Garaud
OrganisationsInstitut Jules Bordet
Molecular Immunology Unit