In silico methods in biofluid transport and biomechanics

Scope of the method

Alternative method relates to
  • Human health
Alternative method is situated in
  • Basic Research
  • Translational - Applied Research
Type of alternative method
  • In silico
This method makes use of
  • Animal derived cells / tissues / organs

Description

Method keywords
  • computational models
  • finite element modeling
  • computational fluid dynamics
  • mass transport
Scientific area keywords
  • biofluids
  • soft tissue biomechanics
  • blood flow
  • drug transport
  • drug administration
  • cardiovascular
  • arterial stiffness
  • medical devices
Method description

The scope of our research ranges from the study of flow and transport processes in blood and biological fluids in the cardiovascular system and artificial organs to biomechanical aspects of the cardiovascular and the skeleto-muscular system and medical devices. All research tracks explored by our past and present Master and PhD students relate to the study of (fluid) mechanical aspects of and transport processes in a native organ or system, in artificial organs and prosthetic devices. We hereby strive towards integration of research at different levels - often starting from a clinical problem or question - and combining computer modelling (from simple lumped parameter models to full 3D-simulation of biomechanical and fluid-structure interaction problems), experimental (hydraulic and test bench) work and in vivo data to explore and unravel the problem. As such, our work combines basic engineering with applied biomedical and clinical research. The final goal can be a better understanding of a patho-physiological problem, a better quantification (and diagnosis) of the function of an (artificial) organ or system, or design of new or improved medical devices for a better patient treatment.

References, associated documents and other information

Associated documents
Links
web-site

Contact person

Patrick Segers

Organisations

Ghent University
Electronics and Information Systems (ELIS)
Belgium
Flemish Region