This method describes the steps from a living mouse to a multi-cellular brain slice model where complex cellular interactions can be evaluated.

Last updated on: 08-11-2019 - 13:14

Contact: Melissa Schepers
Organisation: Hasselt University
Status: Still in development

The cardiorespiratory model reproduces human physiology with a high level of fidelity. It is a lumped parameter model including a representation of atria, ventricles, pulmonary and systemic circulations, autonomic controls, metabolic peripheral control, ventilation and gas exchange in tissues and

Last updated on: 08-11-2019 - 13:04

Contact: Libera Fresiello
Organisation: Cannot be disclosed
Partners: Cannot be disclosed
Status: History of use, Internally validated, Published in peer reviewed journal

Biomechanical modelling used to simulate functional performance of skeleton and muscle systems in vertebrates. For studying how tissues respond to mechanical loading during movement, we apply finite element modelling. For studying how muscles interact with skeletal elements, and how they make

Last updated on: 08-11-2019 - 11:05

Organisation: Ghent University
Partners: Hull University
Status: History of use

In the skillslab, dummy models and simulators are used for teaching various clinical skills such as sutures, injections, … The veterinarians in training start with practising basic skills such as handling animals, and progress over the years to perform more complex procedures on simulators such

Last updated on: 08-11-2019 - 11:02

Organisation: Cannot be disclosed
Status: History of use, Internally validated

The scope of our research ranges from the study of flow and transport processes in blood and biological fluids in the cardiovascular system and artificial organs to biomechanical aspects of the cardiovascular and the skeleto-muscular system and medical devices. All research tracks explored by our

Last updated on: 08-11-2019 - 11:02

Contact: Patrick Segers
Organisation: Ghent University

Functional cardiomyocytes can be efficiently derived from human pluripotent stem cells, which collectively include embryonic and induced pluripotent stem cells (iPSC). Specific affected biological pathways involved in disease can be functionally studied in differentiated cells at a single patient

Last updated on: 08-11-2019 - 11:01

Organisation: Ghent University
Status: Internally validated

The Koken rat is a dummy rat that is developed to train animal procedures, such as handling, blood sampling and intubation.

Last updated on: 08-11-2019 - 10:24

Contact: Cannot be disclosed
Organisation: Cannot be disclosed

The DPRA is an in chemico method which quantifies the remaining concentration of cysteine- or lysine-containing peptide following 24 hours incubation with the test chemical at 25 +/-2,5ºC. The synthetic peptides contain phenylalanine to aid in the detection. Relative peptide

Last updated on: 08-11-2019 - 10:21

Contact: bart Desmedt
Organisation: Sciensano
Partners: Sciensano
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)

The monocyte-activation test (MAT) is used to detect or quantify substances that activate human monocytes or monocytic cells to release endogenous mediators such as pro-inflammatory cytokines, for example tumour necrosis factor alpha (TNFα), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6).

Last updated on: 08-11-2019 - 10:13

Contact: Celine Vanhee
Organisation: Sciensano
Status: Still in development, History of use