Through leveraging our combined computational and biological knowledge, we have proven expertise supporting clients in: (1) Tailored analysis of single-cell data that incorporates relevant biological information, including application of AI and machine learning, (2) Studying the stochastic

Last updated on: 11-03-2024 - 13:31

Contact: Cannot be disclosed
Organisation: BioLizard
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
Through leveraging our combined computational and biological knowledge, we have proven expertise supporting clients in: (1) Evaluating and validating the potential for predictive modeling within your projects, (2) Developing and applying machine learning techniques and other AI-based

Last updated on: 11-03-2024 - 13:31

Contact: Cannot be disclosed
Organisation: BioLizard
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
Through leveraging our combined computational and biological knowledge, we have proven expertise supporting clients in: (1) Developing and applying a range of statistical methods tailored to specific problem settings in both clinical and non-clinical datasets, (2) Integrating multi-omics

Last updated on: 11-03-2024 - 13:30

Contact: Cannot be disclosed
Organisation: BioLizard
Status: History of use, Internally validated, Published in peer reviewed journal, Validated by an external party (e.g. OECD, EURL ECVAM,…)
Adult intestinal stem cells are grown into closed 3D structures with protruding buds and a luminal compartment. These 3D structures are produced from the stem cells present in the base of crypts isolated from rectal mucosa samples that can be collected by suction or forceps biopsy. The crypts are

Last updated on: 22-02-2024 - 11:15

Contact: Anabela Ramalho
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Fiber biopersistence is a key factor in understanding the pathogenicity of man-made vitreous fibres (MMVF). Today, compliance to Note Q in Annex VI of Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures may only be demonstrated via in vivo

Last updated on: 19-12-2023 - 19:17

Contact: Léa Hiéronimus
Organisation: Eurima is the European Insulation Manufacturers Association
Status: Still in development, Internally validated, Published in peer reviewed journal
Endotoxins are lipopolysaccharides anchored at the outer membrane of gram-negative bacteria. These pyrogenic compounds can be introduced in pharmaceutical products during their manufacture and could induce severe physiological reactions in humans. This is why endotoxins are dosed, in order to assure

Last updated on: 28-09-2023 - 11:59

Contact: Flore Laurent
Organisation: Sciensano
Status: Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
In contrast to human medicine, standard imaging techniques for cardiac interventions, namely fluoroscopy, CT and MRI, cannot be used in horses because the size of their thorax is too large for the gantry (CT and MRI) or results in insufficient detail (fluoroscopy). Therefore, echocardiography is

Last updated on: 20-09-2023 - 10:28

Contact: Ingrid Vernemmen
Organisation: Ghent University (UGent)
Status: Still in development
UHDR irradiations show healthy tissue sparing effect known as the FLASH effect. Since 2014, the FLASH effect is investigated worldwide to understand how it works and how to trigger it. The FLASH effect is defined as an in vivo effect. However, in vivo models are often expensive and time-consuming.

Last updated on: 05-09-2023 - 08:45

Contact: Lucas Schoenauen
Organisation: Université de Namur (UNamur)
Status: Still in development
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to assist the calving process in the cow and how to perform artifical insemination and rectal palpation in cows. Although training on living animals is

Last updated on: 28-06-2023 - 13:53

Organisation: Ghent University (UGent)
Status: Still in development, History of use, Internally validated
In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to handle cows and pigs in a correct and safe way. Although training on living animals is indispensable, a part of the training process can be performed on

Last updated on: 28-06-2023 - 13:53

Organisation: Ghent University (UGent)
Status: History of use, Internally validated