We developed in vitro models to study liver disease, such as liver inflammation and fibrosis, as seen in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH); or hepatitis viral infection; or to enhance our ability to detect drugs that cause acute or repeat dose drug induced

Last updated on: 08-11-2019 - 13:32

Contact: Cannot be disclosed
Organisation: KU Leuven
Status: Internally validated, Published in peer reviewed journal
The chorioallantoic membrane (CAM) is a highly vascularized membrane which results from the fusion of two extra-embryonic membranes, namely the chorion and the allantois. The CAM is easily accessible for manipulation and imaging, but methodologies differ whether the chicken embryo stays within its

Last updated on: 08-11-2019 - 13:27

Contact: Hanna Tay
Organisation: Ghent University
Status: Internally validated
Better understanding of molecular mechanisms controlling both normal and malignant human hematopoiesis will lead to a more efficient therapy of immune deficiencies and lymphoid leukemias. Therefore, human hematopoietic progenitor cells (HPCs) are differentiated in vitro towards distinct

Last updated on: 08-11-2019 - 13:21

Contact: Tom Taghon
Organisation: Ghent University
Status: Internally validated, Published in peer reviewed journal
With a one vessel fermentor (BioFlo 110, New Brunswick), an in vitro simulation of a certain part of the gastrointestinal tract (e.g. cecum, colon) is performed. In this fermentation system, physiological gut parameters (pH, temperature) are kept constant, while chemico-physical characteristics of

Last updated on: 08-11-2019 - 13:20

Contact: Marc Heyndrickx
Organisation: Flanders Research Institute for Agriculture
Status: History of use, Internally validated, Published in peer reviewed journal
This method describes the steps from a living mouse to a multi-cellular brain slice model where complex cellular interactions can be evaluated.

Last updated on: 08-11-2019 - 13:14

Contact: Melissa Schepers
Organisation: Hasselt University
Status: Still in development
Biomechanical modelling used to simulate functional performance of skeleton and muscle systems in vertebrates. For studying how tissues respond to mechanical loading during movement, we apply finite element modelling. For studying how muscles interact with skeletal elements, and how they make them

Last updated on: 08-11-2019 - 11:05

Organisation: Ghent University
Partners: Hull University
Status: History of use
In the skillslab, dummy models and simulators are used for teaching various clinical skills such as sutures, injections, … The veterinarians in training start with practising basic skills such as handling animals, and progress over the years to perform more complex procedures on simulators such as

Last updated on: 08-11-2019 - 11:02

Organisation: Cannot be disclosed
Status: History of use, Internally validated