Polycaprolactone (PCL) fiber materials are fabricated using an electrospinning method. Molecular weight of PCL is 45 000 Da (Sigma-Aldrich). The electrospinning process is performed using 18wt% PCL solution dissolved in chloroform:ethanol at a ratio of 9:1. Two high-voltage sources are used to
Last updated on: 23-07-2025 - 09:50
For the generation of the human skin-derived precursors (hSKP) spheroids, ultra-low attachment 96-well plates, cell-repellent (Greiner) are used. hSKP cultured on tissue culture plates are detached with trypple (5 minutes) and collected in a tube. After centrifugation, hSKP are counted at the Burker
Last updated on: 23-07-2025 - 09:50
Contact: Robim Rodrigues
Organisation: Vrije Universiteit Brussel (VUB)
Status: Still in development
Drug-induced phospholipidosis (DIPL) is a metabolic disorder characterized by an excessive intracellular accumulation of phospholipids caused by cationic drugs. Hepatic cells derived from human skin are evaluated as an in vitro model to investigate DIPL and its mechanisms. Human skin stem cells
Last updated on: 23-07-2025 - 09:49
Contact: Cannot be disclosed
Organisation: Vrije Universiteit Brussel (VUB)
Status: History of use
The large (1mm diameter), easily accessible eggs of the frog Xenopus laevis (100-1000 eggs at once per frog) offer the opportunity to reconstitute cell cycle events in-vitro by generating cell-free extracts which retain all the biochemical components that regulate cell cycle progression, as well as
Last updated on: 22-07-2025 - 09:40
Contact: Martina Boiardi
Organisation: Katholieke Universiteit Leuven (KUL), Cellular and Molecular Medicine - KU Leuven
Status: History of use, Published in peer reviewed journal
This method/PhD project explores an innovative approach using synthetic communities (SynComs) to develop vaginal therapeutics. First, a top-down approach will be used to screen and select consortia of vaginal microbiota, emphasizing synergistic interactions and eliminating antagonistic effects. A
Last updated on: 16-07-2025 - 10:51
Contact: Maline Victor
Organisation: University of Antwerp (UAntwerpen)
Status: Still in development
We developed a biventricular statistical shape model (SSM) from high-resolution cardiac CT scans from 271 healthy individuals. Leveraging the diversity captured by our biventricular SSM, we created a synthetic cohort of anatomically detailed, high-resolution, biventricular meshes. The geometries in
Last updated on: 16-07-2025 - 10:01
Contact: Lore Van Santvliet
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Generation of cortical organoids from patient and control hIPSC.
Last updated on: 16-07-2025 - 10:01
Contact: Sarah Weckhuysen
Organisation: Vlaams Instituut voor Biotechnologie (VIB), University of Antwerp (UAntwerpen)
Status: Internally validated
We generate iPSC derived neurons and astrocytes using NgN2, ASCL1 and SOX9 overexpression respectively.
Last updated on: 16-07-2025 - 10:00
Contact: Sarah Weckhuysen
Organisation: Vlaams Instituut voor Biotechnologie (VIB), University of Antwerp (UAntwerpen)
Status: Published in peer reviewed journal
We use HD-MEA recordings from hIPSC derived neuronal cultures to study network behavior of mutant and control cultures.
Last updated on: 16-07-2025 - 10:00
Contact: Sarah Weckhuysen
Organisation: Vlaams Instituut voor Biotechnologie (VIB), University of Antwerp (UAntwerpen)
Status: Published in peer reviewed journal
Studying spermatogenesis in situ has led to the understanding that the 3D reorganization of testicular cells into an interstitial and tubular compartment is of enormous importance for germ cell differentiation. We will rely on 3D bioprinting technology which gives control over cell deposition and
Last updated on: 08-07-2025 - 10:26
Contact: Yoni Baert
Organisation: Vrije Universiteit Brussel (VUB)
Status: Still in development, Published in peer reviewed journal
