The lab routinely use C. elegans culture as genetic model. We explore the development and the ageing of the neuromuscular system. The methods used regularly in our lab include molecular biology, generation of transgenic animals or mutants, crossings, genetic screen, calcium imaging, fluorescence

Last updated on: 02-12-2019 - 13:54

Contact: patrick laurent
Organisation: Université libre de Bruxelles
Status: Internally validated, Published in peer reviewed journal

The Galleria mellonella assay makes use of larvae of the Greater Wax Moth. G. mellonella larvae are injected with a small amount of microorganisms, and survival can easily be followed for up to 1 week. This allows to compare virulence between different organisms. Alternatively,

Last updated on: 08-11-2019 - 13:58

Contact: Tom Coenye
Organisation: Ghent University
Status: Published in peer reviewed journal

The C. elegans assay can be used to study the virulence of various microorganisms, and can be used to evaluate the antimicrobial effect of drugs or drug candidates. The two main outcome parameters are (i) survival of C. elegans and (ii) microbial load.

Last updated on: 08-11-2019 - 13:57

Contact: Tom Coenye
Organisation: Ghent University
Status: Published in peer reviewed journal

The chorioallantoic membrane (CAM) is a highly vascularized membrane which results from the fusion of two extra-embryonic membranes, namely the chorion and the allantois. The CAM is easily accessible for manipulation and imaging, but methodologies differ whether the chicken embryo stays within

Last updated on: 08-11-2019 - 13:27

Contact: Hanna Tay
Organisation: Ghent University
Status: Internally validated