Identifying drug-target interactions is a crucial step in drug repositioning, the process of suggesting new indications for known drugs. There are about 9000 FDA-approved and experimental small molecule drugs and more than 500.000 protein records available. Performing in vitro

Last updated on: 06-01-2020 - 17:04

Contact: Daniele Parisi
Organisation: KU Leuven
Partners: Biotech/TU-Dresden, Max-Planck-Institut für Informatik Saarbrucken
Status: Still in development

Aortic aneurysms consist of a localized dilatation of the aorta resulting from compromised structural integrity and are characterized by a diameter increase of at least 50% compared to a reference diameter. When left untreated, aneurysms tend to progressively enlarge, with an increased risk of

Last updated on: 08-11-2019 - 14:11

Contact: Nele Famaey
Organisation: KU Leuven, KU Leuven
Partners: KU Leuven, KU Leuven , KU Leuven
Status: Still in development, Published in peer reviewed journal

This work will be based on data describing the rat hindlimb kinematics obtained by X-Ray Reconstruction of Moving Morphology (XROMM) and ground reaction forces following destabilization of the medial meniscus (DMM) and running. These data will be analyzed with multi-body dynamics to estimate the

Last updated on: 08-11-2019 - 14:02

Contact: Judith Piet
Organisation: KU Leuven
Status: Still in development

Prototyping and replication (small series production) of microfluidic or optofluidic devices, in thermoplastic polymers or in glass. 3D nanoprinting is also available to produce microscaffolds, possibly within microfluidic channels.

Last updated on: 08-11-2019 - 13:36

Contact: Jürgen Van Erps
Organisation: Vrije Universiteit Brussel
Status: Internally validated, Published in peer reviewed journal

Biomechanical modelling used to simulate functional performance of skeleton and muscle systems in vertebrates. For studying how tissues respond to mechanical loading during movement, we apply finite element modelling. For studying how muscles interact with skeletal elements, and how they make

Last updated on: 08-11-2019 - 11:05

Organisation: Ghent University
Partners: Hull University
Status: History of use

The scope of our research ranges from the study of flow and transport processes in blood and biological fluids in the cardiovascular system and artificial organs to biomechanical aspects of the cardiovascular and the skeleto-muscular system and medical devices. All research tracks explored by our

Last updated on: 08-11-2019 - 11:02

Contact: Patrick Segers
Organisation: Ghent University