Through leveraging our combined computational and biological knowledge, we have proven expertise supporting clients in: (1) Tailored analysis of single-cell data that incorporates relevant biological information, including application of AI and machine learning, (2) Studying the stochastic

Last updated on: 11-03-2024 - 13:31

Contact: Cannot be disclosed
Organisation: BioLizard
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
Endotoxins are lipopolysaccharides anchored at the outer membrane of gram-negative bacteria. These pyrogenic compounds can be introduced in pharmaceutical products during their manufacture and could induce severe physiological reactions in humans. This is why endotoxins are dosed, in order to assure

Last updated on: 28-09-2023 - 11:59

Contact: Flore Laurent
Organisation: Sciensano
Status: Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
Spheroids are three-dimensional cellular models with widespread basic and translational application across academia and industry. However, methodological transparency and guidelines for spheroid research have not yet been established. The MISpheroID Consortium developed a crowdsourcing knowledgebase

Last updated on: 11-02-2022 - 10:29

Contact: Olivier De Wever
Organisation: Ghent University (UGent)
Status: Published in peer reviewed journal
In the early phases of the design cycle of structural heart devices, choosing which prototype to develop can be complicated. There are a lot of unknowns to contend with. FEops’ simulation technology helps fill in these blanks. It gives product developers computational simulations that let them

Last updated on: 01-02-2022 - 13:17

Contact: Cannot be disclosed
Organisation: FEops
Status: Published in peer reviewed journal
Worldwide, outdoor air pollution is responsible for 4.2 million premature deaths per year. Both chronic and acute exposure to particulate matter air pollution is a risk factor for heart and lung diseases. One of the atmospheric pollutant particles is represented by soot or black carbon (BC)

Last updated on: 15-11-2019 - 16:16

Contact: Eva Bongaerts
Organisation: University of Hasselt (UHasselt)
Partners: University of Hasselt (UHasselt), Katholieke Universiteit Leuven (KUL)
Status: History of use, Internally validated, Published in peer reviewed journal
Hyper Polarized (HP) MR allows to considerably increase the sensitivity (>10.000) of MR spectroscopy and spectroscopic imaging. The hyperpolarized molecule can be injected at room temperature to a cell system or an in vivo model and its metabolism can be followed over a few minutes.The technique

Last updated on: 08-11-2019 - 13:56

Organisation: Université Catholique de Louvain (UCL)
Status: Published in peer reviewed journal