A battery of in vitro genotoxicity assays is currently used to detect agents with DNA damaging and carcinogenic potential. Although the sensitivity of this battery of genotoxicity assays is high, the specificity is low (“false positive hit”), especially with the mammalian cell-based assay, compared

Last updated on: 11-07-2022 - 15:51

Contact: Marc Audebert
Organisation: Institut national de la recherche agronomique (INRAE)
Status: History of use, Internally validated, Published in peer reviewed journal, Currently submitted for further validation by an external party (e.g. OECD, EURL ECVAM,…)
Maaike Vercauteren developed the innovative in vitro 'two-chamber skin explant model'. Pieces of skin are kept and examined in a controlled laboratory environment. This is no sinecure, because the skin must continue to function as if it were still attached to the fish. However, the tested setup

Last updated on: 22-02-2022 - 15:13

Contact: Cannot be disclosed
Organisation: Instituut voor Landbouw-, Visserij- en Voedingsonderzoek (ILVO), Ghent University (UGent)
Status: Internally validated
Reflex tests on fish which are used to determine the stress state and survival rate after discards must be correctly conducted and interpreted, and therefore require training. Thanks to ILVO research on the use of video and crowdsourcing (product improvement based on the knowledge and skills of

Last updated on: 07-02-2022 - 09:25

Contact: Cannot be disclosed
Organisation: Instituut voor Landbouw-, Visserij- en Voedingsonderzoek (ILVO), NOAA
Status: Published in peer reviewed journal
With a one vessel fermentor (BioFlo 110, New Brunswick), an in vitro simulation of a certain part of the gastrointestinal tract (e.g. cecum, colon) is performed. In this fermentation system, physiological gut parameters (pH, temperature) are kept constant, while chemico-physical characteristics of

Last updated on: 08-11-2019 - 13:20

Contact: Marc Heyndrickx
Organisation: Instituut voor Landbouw-, Visserij- en Voedingsonderzoek (ILVO)
Status: History of use, Internally validated, Published in peer reviewed journal