Better understanding of molecular mechanisms controlling both normal and malignant human hematopoiesis will lead to a more efficient therapy of immune deficiencies and lymphoid leukemias. Therefore, human hematopoietic progenitor cells (HPCs) are differentiated in vitro towards distinct

Last updated on: 08-11-2019 - 13:21

Contact: Tom Taghon
Organisation: Ghent University (UGent)
Status: Internally validated, Published in peer reviewed journal
With a one vessel fermentor (BioFlo 110, New Brunswick), an in vitro simulation of a certain part of the gastrointestinal tract (e.g. cecum, colon) is performed. In this fermentation system, physiological gut parameters (pH, temperature) are kept constant, while chemico-physical characteristics of

Last updated on: 08-11-2019 - 13:20

Contact: Marc Heyndrickx
Organisation: Instituut voor Landbouw-, Visserij- en Voedingsonderzoek (ILVO)
Status: History of use, Internally validated, Published in peer reviewed journal
This method describes the steps from a living mouse to a multi-cellular brain slice model where complex cellular interactions can be evaluated.

Last updated on: 08-11-2019 - 13:14

Contact: Melissa Schepers
Organisation: University of Hasselt (UHasselt)
Status: Still in development
Functional cardiomyocytes can be efficiently derived from human pluripotent stem cells, which collectively include embryonic and induced pluripotent stem cells (iPSC). Specific affected biological pathways involved in disease can be functionally studied in differentiated cells at a single patient

Last updated on: 08-11-2019 - 11:01

Organisation: Ghent University (UGent)
Status: Internally validated